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3, so it was not likely that there was multicollinearity while in the numerous linear regression models. Also, we performed sensitivity analyses by making use of urinary creatinine concentration (log-transformed) being a covariate as an alternative to creatinine-adjusted urinary significant metal concentrations and which include interaction conditions in between possibly toxic significant metals (As, Cd, and Pb) or Se; none of the urinary creatinine focus as well as the conversation conditions was statistically important, and overall associations involving urinary hefty metals and blood pressure level did not alter (Tables S1 and S2).
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一般社団法人 日本プライマリ・ケア連合学会予防医療・健康増進委員会 予防医療チーム
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The main toughness of the review was the urine samples have been collected in seventeen communities with several features throughout four Asian nations; this enabled an independent investigation of associations in between urinary heavy metallic concentrations and blood pressure level with the regional degree. Study limits bundled measuring the full As concentrations from the urine samples with out speciation Assessment to distinguish among publicity to poisonous inorganic As and non-harmful natural and organic As compounds. Additionally, we assessed large steel exposure degrees making use of solitary place urine samples. To evaluate the systemic physique burdens of Pb and Se, it might are actually useful to look at their concentrations in complete blood, erythrocytes, or serum/plasma samples [seventy one, 72].
Figure 1 demonstrates the results of a number of linear regression analyses that evaluated the associations amongst urinary major metal concentrations and hypertension in Every nation (see Table S3 for specifics). Associations amongst website urinary Cd concentrations and hypertension differed by place: urinary Cd concentrations were being positively related to SBP and DBP in Nepal, although urinary Cd concentrations have been negatively connected to SBP and DBP in Bangladesh.
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症状を訴えて私たちへ助けを求めて来る患者に対して、私たちは最善を尽くすことは約束しても、利益が害を
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東京大学医学部先進循環器病学講座 特任講師。医師。医学博士。総合内科専門医。循環器専門医。ライフワークとして継続してきた予防医学の研究・臨床を社会実装することを目指している。慶應義塾大学医学部卒業。 社外取締役 大西 勝也